It seems like a parsimonious state-space for a drug would just be the agonistic/antagonistic affinity for every neuro-receptor. There would be some partial coronations (between all of the subtypes of the GABA receptor for example).
It would be neat to see how the authors psychological state-space and this neuro state-space map to each other though.
> just be the agonistic/antagonistic affinity for every neuro-receptor
Except that pretty much every receptor subtype, every transporter protein and many other brain genes exist in multiple variations in the human population, and those variations do alter the way these proteins act. This is one reason why different drugs affect different people differently, because at the lowest level, you don't have the same brain chemistry as other people, there are an infinite number of possible variants.
It would be neat to see how the authors psychological state-space and this neuro state-space map to each other though.